AstraZeneca to build drug substance manufacturing facility in Virginia

AstraZeneca to build drug substance manufacturing facility in Virginia

Aug. 21, 2025
The company’s investment is part of a broader $50 billion commitment to U.S. manufacturing and R&D by 2030.

AstraZeneca has announced plans to build a new drug substance manufacturing facility in the Commonwealth of Virginia. The company, which develops and produces innovative medicines for a range of diseases, has invested a multi-billion dollar sum into the project, which is expected to create hundreds of highly skilled new jobs.
 
The planned facility will be AstraZeneca’s largest single manufacturing investment globally and will support production of drug substances for its weight management and metabolic portfolio, including oral GLP-1, baxdrostat, oral PCSK9, and combination small molecule products. The site will manufacture small molecules, peptides, and oligonucleotides, and will integrate technologies such as AI, automation, and data analytics to optimize production.
 
This investment is part of AstraZeneca’s $50 billion commitment to expand its U.S. R&D and manufacturing footprint by 2030. Additional investments include expansions and new facilities across Maryland, Massachusetts, Indiana, Texas, and California.

What people are saying 

In a recent quote, Pascal Soriot, Chief Executive Officer, AstraZeneca, said, “Today’s announcement underpins our belief in America’s innovation in biopharmaceuticals and our commitment to the millions of patients who need our medicines in America and globally. It will also support our ambition to reach $80 billion in revenue by 2030. I look forward to partnering with Governor Youngkin and his team to work on our largest single manufacturing investment ever. It reflects the Commonwealth of Virginia’s desire to create highly skilled jobs in science and technology, and will strengthen the country’s domestic supply chain for medicines."

Governor Glenn Youngkin, Commonwealth of Virginia, added, “I want to thank AstraZeneca for choosing Virginia as the cornerstone for this transformational investment in the United States. This project will set the standard for the latest technological advancements in pharmaceutical manufacturing, creating hundreds of highly skilled jobs and helping further strengthen the nation's domestic supply chain. Advanced manufacturing is at the heart of Virginia's dynamic economy, so I am thrilled that AstraZeneca, one of the world's leading pharmaceutical companies, plans to make their largest global manufacturing investment here in the Commonwealth.”

Manufacturers investing in Virginia

Verne invests $4.5M to open hydrogen storage vessel manufacturing facility in Pennsylvania
The new facility will create at least 61 full-time jobs and strengthen Pennsylvania’s clean energy and advanced manufacturing sectors. 

Micron Technology invests $30B to expand memory manufacturing facilities in Idaho and Virginia
The expanded production will help meet increasing demand driven by AI and support Micron’s goal of producing 40% of its DRAM in the U.S.

Nightingale Ice Cream Sandwiches invests $5.8M to open ice cream manufacturing facility in Virginia 
The company’s new location will also serve as its corporate headquarters as it expands operations in Richmond. 

Investing in American manufacturing in 2025 

This map shows where manufacturers are choosing to invest their resources, whether they are building new production facilities or expanding existing plants. 

About the Author

Thomas Wilk | editor in chief

Thomas Wilk joined Plant Services as editor in chief in 2014. Previously, Wilk was content strategist / mobile media manager at Panduit. Prior to Panduit, Tom was lead editor for Battelle Memorial Institute's Environmental Restoration team, and taught business and technical writing at Ohio State University for eight years. Tom holds a BA from the University of Illinois and an MA from Ohio State University

Sponsored Recommendations

April 14, 2025
This paper addresses where leaks commonly occur, leak detection methods, and practical advice for an audit and repair plan. You'll learn why an ongoing leak detection and repair...
April 14, 2025
This special report explores the latest innovations in compressed air tech to help your facility reduce artificial demand and achieve greater system control. You'll also gain ...
April 14, 2025
Here are some things you can do in between formal preventive maintenance visits on your electric screw compressor to extend compressor life and prevent downtime.
April 14, 2025
They cost more than refrigerated dryers. They need more parts and service than refrigerated dryers. They increase demand for compressed air. So when should you use a desiccant...