Merck invests $1B to build biologics manufacturing facility in Delaware 

Merck invests $1B to build biologics manufacturing facility in Delaware 

May 12, 2025
The new site will include laboratory, manufacturing, and warehouse capabilities to support next-generation biologics and therapies. 

Merck has announced plans to build a biologics manufacturing facility in Wilmington, Delaware. The company, which develops and produces medicines and vaccines, has invested $1 billion in the project, creating more than 500 full-time roles and approximately 4,000 construction jobs. 

Located at the Chestnut Run Innovation & Science Park (CRISP), the 470,000-square-foot facility will be dedicated to manufacturing potent antibody-drug conjugates and other next-generation biologics. It will also have the capability to produce KEYTRUDA (pembrolizumab) for U.S. patients. The laboratory component of the site is expected to be operational by 2028, with production of investigational compounds projected to begin by 2030. 

Merck plans to further expand the facility beyond the initial build, with potential to add another 1,500 full-time positions and up to 26,000 construction jobs. The facility’s location near Delaware and Pennsylvania universities is expected to help attract skilled talent and support regional workforce development. 

What people are saying 

In a recent quote, Robert M. Davis, chairman and chief executive officer, Merck, said, “The Merck Wilmington Biotech site represents our continued commitment to growing our investments in U.S. manufacturing and has the potential to create thousands of high-paying American jobs while ensuring that we can produce and distribute products close to patients right here in the U.S.” 

Matt Meyer, governor, State of Delaware, added, “This new site in Delaware is on the cutting edge of innovation, helping lead the way as we transform medicine and technology. Merck is pioneering the next generation of care right here in Wilmington, and they couldn’t have picked a better place to do it. The positive impact this will have on Wilmington and the state of Delaware is exciting, and this is the just the beginning.” 

Investing in American manufacturing in 2025 

This map shows where manufacturers are choosing to invest their resources, whether they are building new production facilities or expanding existing plants. 

About the Author

Alexis Gajewski | Senior Content Strategist

Alexis Gajewski has over 15 years of experience in the maintenance, reliability, operations, and manufacturing space. She joined Plant Services in 2008 and works to bring readers the news, insight, and information they need to make the right decisions for their plants. Alexis also authors “The Lighter Side of Manufacturing,” a blog that highlights the fun and innovative advances in the industrial sector. 

Sponsored Recommendations

April 14, 2025
Here are some things you can do in between formal preventive maintenance visits on your electric screw compressor to extend compressor life and prevent downtime.
April 14, 2025
They cost more than refrigerated dryers. They need more parts and service than refrigerated dryers. They increase demand for compressed air. So when should you use a desiccant...
April 14, 2025
Follow these ten steps for energy savings in your compressed air system.
April 14, 2025
Whether you are installing a new compressed air distribution system or upgrading an existing one, this e-book will help you identify the best piping materials for your application...